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Forman, H.J., J.M
Despite its clinical utility, 5-FC is prone to rapid resistance development when used as monotherapy
At any rate, the long-term role of NCC either as an ion transporter sensitive to thiazides, as an IL-18 receptor or as a potential partner for GLP-1 receptors in -cells or in any capacity in metabolically active tissue awaits exploration, particularly within the context of obesity, the most prevalent component of MetS
For musculoskeletal applications, this might include pain scores, functional assessments, range of motion measurements, and imaging studies to evaluate structural healing
