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Dohm GL, Elton CW, Raju MS, Mooney ND, DiMarchi R, Pories WJ, Flickinger EG, Atkinson SM Jr, Caro JF

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High dose oral cobalamin would be a reasonable alternative as maintenance in patients unable to tolerate intramuscular injections provided there is good compliance with treatment

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Human research demonstratedthat methylcobalamin supplementation in patients with inadequate B12 levels improved CD4/CD8 ratio and NK cell activity,and augmented CD3-CD16+ cells, suggesting an important role in cellular immunity

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Sonntag WE, Ramsey M, Carter CS

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