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Khan, S

10.1016/j.jtho.2016.10.014 J

Think about how, when youre anxious or scared, your heart starts pumping faster, your breath gets shallow, and you start feeling a little flushedall of which are ways your body primes you to run like hell

114 In the context of ALS, the interaction of CCS with mutant SOD1 is faulty, resulting in decreased delivery of Cu to the mitochondria and the accumulation of the less-stabilized SOD1, which is prone to acquire pro-oxidants, consequently causing a toxic gain-of-function effect in motor neurons
