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Description
Polymyxins (PMs), including polymyxin B (PMB) and colistin (CST, polymyxin E), have been reintroduced for the treatment of infections caused by Gram-negative MDR bacteria due to their strong bactericidal activity [1, 10]
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A phase 2 placebo-controlled study indicated that the dual-acting KOR agonist/MOR antagonist nalbuphine extended-release (ER) tablets effectively treat PN
The maintenance of normal functioning of the brain and nervous system