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Description
In osteoarthritis, fisetin also suppressed IL-1-induced production of TNF-, IL-6, COX-2, iNOS, MMP-3, MMP-13, and ADAMTS-5 via activation of SIRT1 [69,70]
These residues can undergo oxidation to form disulphide bonds and thus reduce PDI or an equivalent ER oxidoreductase
& Madak Erdogan, Z
(7) Clearly, glutathione is a potent antioxidant that is crucial for many essential bodily functions
