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6a), the entire genomic loci of GCLC was showed in Supplementary Fig

Although foetuses at this point are already more developed, they are at risk of being either small or large for gestational age and they tend to have less adaptability and can rapidly deteriorate [35]

For example, overexpression of the BRCP/ABCG2 transporter is associated with resistance to several anti-cancer drugs including doxorubicin, mitoxantrone and topotecan [65], whilst ABCB1/MDR1 is frequently overexpressed in drug-resistant cell lines and is found to correlate with poor overall survival in patients [20, 66]

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