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The binding of antithrombin III to the endothelial surface is also reduced by homocysteine through inhibition of heparin sulfate expression (Nishinaga et al, 1993)
Additionally, human atherosclerosis has been linked to mitochondrial oxidative stress (Petrucci et al., 2022) Mitochondrial ROS are utilized extensively as cellular messengers in signaling cascades
doi: 10.3389/fpsyt.2020.601653 86 VanderbruggenN.MatthysF.LaereS
