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The Ser/Asp/His triad is contained in a hydrophobic groove that is blocked from solvent by the lid

Neuromodulation Although FAO is not a major pathway in brain bioenergetics, carnitine still accumulates in the brain, and in neurons isolated from the adult brain, about 80% of total carnitine remains in free form, while about 1015% is present as acetylcarnitine and about 10% as LCACs [90]

Role of penicillin-binding protein 2 (PBP2) in the antibiotic susceptibility and cell wall cross-linking of Staphylococcus aureus : evidence for the cooperative functioning of PBP2, PBP4, and PBP2A