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It is also important to consider that the identification of cell types responsible for Fc-dependent antibody-mediated protection in mice (and other animal models) does not necessarily translate directly to humans owing to factors including differences in the FcR expression profile of these cells (Table 1) and differences in the relative abundance of these cell types in tissues and in circulation

& Matsuda, S

In some cases, they weaken the immune system, making individuals more vulnerable to infections

Int J Mol Med 42(3):16441652 Han M et al (2023) Spatial mapping of mitochondrial networks and bioenergetics in lung cancer