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Recently, the introduction of genomic, autoradiographic, and proteomic techniques (Guo et al., 2018), as well as advances in chemical speciation (Michalke et al., 2018

BHB, one of the KBs, can also enhance oxidative brain metabolism, resulting in the production of gamma-aminobutyric acid (GABA) (27), GABA B activation (24), the induction of synaptic recycling of glutamate loaded vesicles (24, 28), activation of K ATP (18), activation of two-pore domain potassium channels (K2P) (20), and the decrease of acid-sensing channels (ASICs) (29), thereby dampening neuronal excitability (20)

Pamudurti NR, Bartok O, Jens M, Ashwal-Fluss R, Stottmeister C, Ruhe L, et al

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