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Patients often exhibit structurally abnormal, swollen mitochondria with disrupted cristae, impaired mitochondrial recycling (a process called mitophagy), and chronically elevated levels of reactive oxygen species

doi: 10.1155/2017/2549491 204 NordioMBascianiS

This also precluded accurate t 1/2 determination, indicated as not determined in Table 3

145 (18), e876e894
