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Increased redox stress correlates with loss of mitochondrial respiratory capacity with aging

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Future research should focus on preclinical models that explore these mechanisms, especially in gynecologic malignancies like ovarian, endometrial, and cervical cancers

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These include inhibition of monoamine oxidase (MAO) enzymes, modulation of GABAergic receptors, suppression of neurotransmitter reuptake, regulation of hormonal balance via the HPA axis, enhancement of neurogenesis and synaptic plasticity, and protection against oxidative and inflammatory damage

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Oral Glutathione Gastric acid and intestinal enzymes break down most of the dose before systemic absorption

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