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Skin tumors induced by sorafenib

Of note, the cluster miR-143/145 was further reported to target directly the IGF1R in CRC cells, and provided evidence of a cooperative repression of the IGF1R gene expression by the two miRNAs (87)

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TLK286 clinical effects were investigated in the last decade in phase II and phase III trials for the treatment of drug-resistant ovarian cancer 112,113
