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Earlier, the same group identified a major sex-specific effect of ARKO on hindlimb skeletal muscle mass such that 9-week-old male, but not female, ARKO mice exhibited a 12.6% reduction in total mass and a 2225% reduction in TA, EDL, soleus, and gastrocnemius absolute mass [178]
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The seven distinct classes of soluble GST that are highly expressed in the mammalian liver are comprised of alpha, mu, pi, theta, kappa, sigma, zeta and omega gene families [3]
