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380 Another primary astrocytopathy linked to dysregulated iron homoeostasis is aceruloplasminemia, an autosomal recessive neurodegenerative disease caused by a loss of function mutations of the gene encoding ceruloplasmin, an enzyme that converts ferrous iron to ferric

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erinaceus polysaccharides modification strategies must evolve from empirical exploration to precision design to advance medical and nutraceutical applications
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