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l-carnitine synthesis Asymmetric of from (R)-3-chloro-1,2-propanediol Carnitine Metabolism and Its Role
Description
TMAO is toxic to the kidney and has been shown to have severe implications in the progression of many diseases such as cardiovascular diseases, heart failure, kidney disease, metabolic syndrome, neurological diseases, and some cancers

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[DOI] [PubMed] [Google Scholar] 108.Pagano G., Manfredi C., Pallard F.V., Lyakhovich A., Tiano L., Trifuoggi M

Marked elevation in plasma trimethylamine-N-oxide (TMAO) in patients with mitochondrial disorders treated with oral l-carnitine