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It has been demonstrated that probiotics can indirectly lower oxidative stress by enhancing gut health and lowering inflammation

Neuromolecular Med 17:364372 Tsvetkov P, Coy S, Petrova B, Dreishpoon M, Verma A, Abdusamad M et al (2022) Copper induces cell death by targeting lipoylated TCA cycle proteins

Additionally, ROS acts as secondary messengers in intracellular signaling cascades, modulating cellular processes such as antioxidant gene regulation, cell proliferation and survival, and autophagy [249,250,251]

(4) Methodological limitations: This study employed an ultraviolet enzymatic method to assess serum GR activity