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(252) found that GGT1 levels are significantly increased in ccRCC cell lines (786-O and RCC10), and GGT1 can promote GSH synthesis, preventing ferroptosis caused by lipid peroxidation in tumor cells, thereby promoting tumor cell proliferation and metastasis

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Mod Razif MRF, Chan SY, Chew Y-L, Hassan M, Ahmad Hisham S, Abdul Rahman S et al (2024) Recent developments in luteolin-loaded nanoformulations for enhanced anti-carcinogenic activities: insights from in vitro and in vivo studies