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DMF mediates NRF2-dependent and independent mechanisms on TSS pathway CBS activation DMF activates NRF2, the master regulator for the antioxidative stress response, to regulate the expression of proteins involved in iron hemostasis, and GSH synthesis such as HMOX1, NQO1, FTH, FTL, SLC40A1 in a variety of cellular systems 37
Similarly, dietary supplementation with 1% cholesterol reduces hepatic CYP51A1 mRNA and protein levels in Sprague-Dawley rats
An elevated plus maze (EPM) is a cross-shaped maze with two closed and two open arms installed at a height of 50 cm
(2007) Immunoregulatory effects of homocysteine on cardiovascular diseases
