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Recent studies have reported that hyperandrogenemia induces disorders of glucose and lipid metabolism at the central and peripheral levels, promoting the development and progression of obesity and type 2 diabetes in both female individuals and rodents with PCOS (40, 41)

Lentiviruses expressing these shRNAs were used to infect tumor cells, and subsequently, clone selection was performed using puromycin at a concentration of 2 g/mL

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