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Consistent with negative feedback by p21 on p53 levels (Broude et al, 2007), induction of p21 FL and p21 N , but not p21 C , decreased basal p53 levels and attenuated p53 stabilization upon nutlin-3 treatment, further validating the function of these proteins (Fig 2E)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 233.Khan H., Singh T.G., Dahiya R.S., Abdel-Daim M.M

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In assessing early-stage PD, a consistent finding on brain MRI is reduced signal intensity and atrophy in the SN and putamen (213, 214)

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