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Therefore, in another round of experiments, the following treatments were studied (7 rats/group): BDL + taurine (0.25% w : v in drinking water for 42 consecutive days)

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Upregulation of NCOA4 promotes lysosomal degradation of ferritin, leading to a sharp expansion of the intracellular labile iron pool, which provides the essential iron substrate for ferroptosis and directly lowers the threshold for ferroptosis initiation (83)

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