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Description
GLP-1R agonists have demonstrated the ability to improve cognitive function, reduce hippocampal synaptic loss, and decrease A plaque deposition and A oligomer levels in APP/PS1 transgenic mice [53, 54]
Their "integrated trigger point hypothesis" describes an energy crisis at the motor endplate (the junction where nerve meets muscle)
Sci Rep 14 , 20553 (2024)
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