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The synthetic triterpenoid CDDO-Me blocks survival of neoplastic mast cells and synergizes with KIT D816V-targeting drugs in inducing growth inhibition
doi: 10.1016/j.it.2004.09.015 223 JiJHuSLCuiZWLiWF
NAD+ (nicotinamide adenine dinucleotide), an essential coenzyme present in all living cells, activates sirtuins and supports DNA repair, mitochondrial function, and metabolic regulation -- touching multiple hallmarks simultaneously
