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However, limitations include in vivo instability, reliance on biocompatible and robust carriers and restricted application procedures (local and direct)

GPX2 inversely correlated with expression of multiple pro- inflammatory cytokines/chemokines and NF-kB activation in cell lines and knockdown of GPX2 led to increased secretion of prostaglandin E2 (PGE2) and interleukin-6

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