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Studies investigating drug interactions and their effects on the cytochrome P450 (CYP450) enzymes have all used human primary hepatocytes, Caco2 cells, and liver microsomes

[DOI] [PubMed] [Google Scholar] 79.Buchmuller-Rouiller Y, Corrandin SB, Smith J, et al

Science (2003) 302(5646):8411

Those exploring the combination of semaglutide with B12 are already thinking along the right lines about nutritional support during therapy
