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Additional E11 codes may be appropriate depending on the patient clinical picture: E11.21 - Type 2 diabetes mellitus with diabetic nephropathy E11.36 - Type 2 diabetes mellitus with diabetic cataract E11.40 - Type 2 diabetes mellitus with diabetic neuropathy, unspecified E11.51 - Type 2 diabetes mellitus with diabetic peripheral angiopathy without gangrene Listing all applicable diabetes complication codes strengthens the medical necessity case and helps justify tirzepatide over less expensive alternatives

Your dose needs may be different during pregnancy or while you are nursing

The combination of multiple medications affecting gastrointestinal motility should be carefully evaluated, and patients should be monitored for both efficacy and tolerability

High doses too frequently may lead to rare side effects like low potassium or vascular stress