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Because phosphorylated signal transducer and activator of transcription (STAT) 3 (pSer727) was also increased in the resistant HCC cells, treatment with a small-molecule STAT inhibitor reverted the phosphorylation and subsequent mitochondrial protein alterations, enhancing sensitivity to sorafenib (Pandit et al., 2021)

Propionic acid induces cytoskeletal alterations in cultured astrocytes from rat cerebral cortex
