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Depletion of tryptophan (a Candida metabolic substrate) reduces serotonin synthesis, while chronic gut inflammation elevates inflammatory cytokines (IL-6, TNF-) that independently suppress mood via neuroinflammatory pathways

Cell 177 , 18881902.e21 (2019)

Similar content being viewed by others Introduction Parkinsons disease (PD) is the second most common neurodegenerative disorder, affecting over 6 million people worldwide 1 , with a marked increase in prevalence in the past 30 years 1

without compartment-targeted reporters, source/localization attribution is lost