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Cysteinylglycine or -glutamylcysteine have been proposed as possible alternatives.In a trial of adolescents with poorly controlled type 1 diabetes, a dose of 30-45mg/kg/day NAC failed to correct several markers of glutathione status, suggesting either a higher dose or alternative therapies may be indicated in this population.A recent study of patients with poorly controlled type 2 diabetes found that dietary supplementation of the amino acids cysteine and glycine, markers of glutathione synthesis and plasma oxidative stress were both improved

RF and SJ designed the studies

Exp Eye Res 90:376381

Research suggested that cannabidiol (CBD) and cannabis-based therapies may protect against oxidative stress, potentially reducing inflammation and cell damage in the chronic wound microenvironment and the surrounding tissues [13,14]