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In other words, as fatigue is usually provoked by a motor or cognitive activity, not knowing the nature of this activity poses a gap in understanding how and when fatigue caves in

Molecular analyses showed that CO23RFLC had acquired a marked increased expression of the MDR1 gene encoding for an efflux pump protein mainly responsible for the drug-resistance, due to a mutation in the transcription factor gene MRR1 [16] whereas CO23RFK had a homozygous mutation (S645Y substitution) in the FSK1 gene, responsible for the synthesis of glucan [17]

To evaluate these advantages, Prabhath et al

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