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In addition to the removal of necrotic debris 46,47,48,49,50 , the recruited macrophages excrete TGF- through which they stimulate senescence 14 and mitogens such as interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-) that trigger proliferation 51,52,53,54
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H.GeJ.ChenJ.et al
Niketa Sonawane for treatment of hyperpigmentation and acne, and I couldn't be happier with the results
