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Thus, ()-huperzine A (1) and (+)-huperzine A ( ent -1) inhibited the binding of MK-801 in the cerebral cortex of rats with similar potencies (IC 50 values of 65 7 M and 82 12 M for ()- and (+)-1, respectively [means SEM, n = 5 for each isomer])

[21] did not show any modification in the content of carnitine in the muscle after a single intravenous dose of 185 mol/kg

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