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95 showed that dietary antioxidant supplementation with vitamin E slowed the onset of dementia in patients with AD
The figure below shows the mechanism of NAPQI generation and its further metabolism, as well as the possible mechanism of NAC in removing NAPQI
Furthermore, glutamine-derived fumarate, malate, and citrate are significantly increased when glucose is deprived, demonstrating that glutamine drives the glucose-independent TCA cycle in a nutrient-poor tumor microenvironment (Le et al., 2012)
