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Cancer Res 71:946954 Yokoyama C, Sueyoshi Y, Ema M, Mori Y, Takaishi K, Hisatomi H (2017) Induction of oxidative stress by anticancer drugs in the presence and absence of cells

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Preclinical studies indicate that metformin promotes M2 macrophage polarization through STAT6 activation, which facilitates tissue repair and attenuates TGF-1-mediated renal fibrosis (109)

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