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Description
Perioperative BPC-157 administration in surgical patients represents a potential application requiring safety and efficacy validation in clinical trials with surgical outcome measures

This approach is essential for enhancing the translational relevance of preclinical research

Outside the CNS, serotonin is produced in the ENS and released predominantly by enterochromaffin cells (estimated to be up to 90% of the body's serotonin production [169]) of the gut mucosa and immune cells, with influence not only on the ENS but also on the CNS via the GBA [283]

PMID: 41252251 Cell Rep 2025 Aug 5;44(8):116112
