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WARNINGS: Patients with early Leber's disease (hereditary optic nerve atrophy) who were treated with cyanocobalamin suffered severe and swift optic atrophy

Lefort K, Ostano P, Mello-Grand M, Calpini V, Scatolini M, Farsetti A, et al

The deletion of GCS1 , an ortholog of mammalian ArfGAP1, was originally identified as a suppressor of human LRRK2-induced cellular toxicity in yeast (Xiong et al., 2010)

Interestingly, researchers have also identified potential mechanisms by which tobacco damages fertility
