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Fluorescence density of PAMAM-PEG-Tf/TMZ in TfR+ glioma stem cells (GSCs) was significantly higher than that of matched non-stem cells and active apoptosis of tumor cells could be observed after the uptake of PAMAM-PEG-Tf/TMZ, suggesting that targeting transferrin receptors to deliver TMZ is a potential GSC-mediated treatment method (182)

Shahnawaz M, Mukherjee A, Pritzkow S, Mendez N, Rabadia P, Liu X, Hu B, Schmeichel A, Singer W, Wu G, Tsai A-L, Shirani H, Nilsson KPR, Low PA, Soto C (2020) Discriminating -synuclein strains in Parkinsons disease and multiple system atrophy

Weight in Parkinsons disease: phenotypical significance

185,186 However, its benefit remains uncertain, with conflicting findings from clinical trials