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As the 2 nd most common neurodegenerative disease after Alzheimers disease, PD poses significant clinical and socioeconomic burdens 2

The authors showed through a luciferase assay that miR-532 targeted directly IGF1R and, consistently, miR-532 expression levels were negatively correlated with IGF1R levels in CRC tissues

Conversely, fungal exosomes hold promise as vaccines: their specific components (e.g., mannan, glucan) can interact with TLR4 and Dectin-1 on immune cells, offering a potential strategy for combating or preventing candidiasis (Honorato et al., 2024)

( G L ) Representative immunoblots ( F ) and densitometric analysis of PGC1 ( G and H ), SIRT1 ( G and I ), and -ACTIN protein levels, cardiac Ppargc1a , Pparg , Sirt1 , carnitine palmitoyltransferase 1- ( Cpt1b ), acyl-CoA oxidase 1 ( Acox1 ), uncoupling protein 2 ( Ucp2 ), Ucp3 , angiopoietin-like-4 ( Angptl4 ), lipoprotein lipase ( Lpl ), natriuretic peptide B ( Nppb ), actin 1 ( Acta1 ), natriuretic peptide type A ( Nppa ), and collagen type I 1 chain ( Col1a1 ) mRNA levels ( J )