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In GBM, elevated IDO1 expression correlates with tumor progression and poor prognosis, partly by suppressing ferroptosis via stabilizing SLC7A11 mRNA through FTO-dependent m6A methylation [89]

Sawka AM, Cappola AR, Peeters RP, Kopp PA, Bianco AC, Jonklaas J

Wu et al ., 2024)

The MAPK and Akt inhibitors, UO126 and Akt inhibitor VIII respectively, were used to determine to what extent, if any, activation of their targets is required for Dihexa-mediated protection
