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These coactivators generally orchestrate with DNA-bound transcription factors, such as nuclear respiratory factors (NRF1, NRF2), estrogen-related receptors (ERR, ERR, and ERR), and myocyte enhancer factor 2 (MEF2) to drive the expression of target genes
Many patients using semaglutide for diabetes or weight management wonder whether they can safely combine it with ashwagandha, a popular herbal supplement for stress relief

The nervous system rapidly regulates organ interactions through pathways such as the vagus nerve, 17,18 whereas the endocrine system transmits information across multiple organs via hormonal signals such as insulin and cortisol
[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Demirbag R., Yilmaz R., Erel O