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Furthermore, it has been recently suggested that this factor could hold a negative prognostic significance in BC ( Plasma Levels of IGF-1 and Breast Cancer The concentrations of IG1 in plasma are approximately 150400 ng/mL, where it is present mostly as protein-bound form ( Many different factors affect IGF-1 plasma concentrations: GH activity, nutritional status, sex, estrogen levels, and age ( in vitro studies demonstrated that IGF-1 stimulates the growth of human BC cell lines (Sasi et al., 2014

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Curcumin upregulates Nrf2 nuclear translocation and protects rat hepatic stellate cells against oxidative stress

doi: 10.1007/s11064-016-1837-9