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Description
GSH depletion increased cytosolic ROS (Fig
GPX4 catalyzes the reaction of GSH with ROS and lipid peroxides to form GSSG, which protects cells from ferroptosis 11

Additional documented functions include the biosynthesis of vitamins, the metabolism and deconjugation of bile salts, diverse enzymatic activities that contribute to nutrient bioavailability, and the neutralization of dietary or microbial toxins ( Probiotics also support intestinal electrolyte absorption, influence lipid metabolism, and can bind directly to Gram-negative pathogens

[DOI] [PubMed] [Google Scholar] 98.Chatterjee I.B., Gupta S.D., Majumder A.K., Nandi B.K., Subramanian N