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Description
SLC7A11/xCT in cancer: biological functions and therapeutic implications

Excessive ROS could cause cells to undergo ferroptosis and accompany a series of changes in cell morphology, such as outer membrane rupture, nuclear integrity, reduction of mitochondrial ridges, and membrane condensation ( Recent studies have found that the loss of histone deubiquitinase MYSM1 can induce ferroptosis and affect the function of hematopoietic stem cell, providing a new clinical approach for treating complex blood diseases (Zhao et al., 2023)

doi: 10.1016/j.jep.2021.113810
Jarow, J
