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In one of these studies, measuring brain GSH levels with in vivo proton MRS yielded a correlation in GSH reduction and decline in cognitive functions with 87.5% sensitivity and 100% specificity (Mandal et al., 2015)

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From a safety perspective, SC administration of apomorphine may cause injection site reactions such as bruising (16%), granulomas (4%) or itching (2%), but these typically do not lead to discontinuation ( 5% of patients) [9]