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TAT peptide is also commonly used as a control peptide by other research groups [68,69,70] as well as our research group [71, 72]

We find that ArfGAP1 proteins containing residues 137415 and 252359 are robustly phosphorylated by G2019S LRRK2 and to a lesser extent by WT LRRK2, relative to kinase-inactive D1994A LRRK2 or in the absence of LRRK2 (Figures 1C,G)

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The more tooth loss there is and the deeper the filling, the greater the risk to the nerve for sensitivity, pain, and nerve loss (death of the nerve)