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BMJ 2015, 351 , h4183

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A study showed that supplementation with phospholipidated curcumin (500 mg/day, twice daily) and glucosamine (500 mg/day Regenasure, twice daily) improved the Karnofsky index, the WOMAC score, and treadmill walking distance in patients with osteoarthritis of the knee

Such inhibition of NF-B signaling was closely associated with a decrease in levels of interleukin-6 and monocyte chemoattractant protein-1