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PLS-DA identified five peptides with a VIP coefficient greater than 2.00 and a p-value less than 0.05 from both a BH-corrected t test and a Wilcoxon rank-sum test (Fig
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In cases of more caudal or more cephalad maximal extrusions, this measurement is taken from the posterior edge of the vertebral cortex/endplate instead of the disc
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