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The released Mn (4+) can also deplete intracellular GSH to stimulate Fenton-like reactions, sensitizing tumor cells to ferroptosis ( 2+ ions and inhibits the AKT/mTOR signaling pathway to downregulate GPX4, thereby inducing tumor cell ferroptosis (Xia Y

37,38 Previous studies share many similarities with our study regarding the effects of GABA on gut microbiota and glutamate metabolism, particularly in promoting the growth of GABA-producing bacteria and regulating glutamate-GABA balance

Would M6G be expected to have good oral bioavailability