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Altered GABAergic Neurotransmission in Schizophrenia GAD67 in Schizophrenia One of the most consistent postmortem findings in schizophrenia is a reduction of mRNA encoding for GAD67 in the dorsolateral prefrontal cortex (DLPFC) in layers 1 through 5 (35, 1629), which results in a reduction of GAD67 protein levels although this has been less extensively studied (Table 1) (4, 30, 31)

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